The 39-year-old dined out at Covent Garden's restaurant Balthazar with the female Friday evening, reports dailymail.co.uk.
Brand wore a black shirt and fitted leather trousers and completed the look with a pair of grey Chelsea boots. After dinner, the couple made their way to trendy Clove Club.
The British star also posed for a photo with three young fans.
The versatile actor, writer, comedian and activist is believed to be single following the reported demise of a previously blossoming relationship with 40-year-old Khan.
Brand, Khan have unfollowed each other on micro-blogging site Twitter.