The 71-year-old actor will be seen sharing screen with Farhan Akhtar and Aditi Rao Hydari in the movie about a chess player.
"Vinod Chopra produces the first shot of the film we do together, directed by Bejoy Nambiar, with Farhan Akhtar and Aditi Rao Hydari and as per tradition the first day and its shots are never to anyone's satisfaction. We are no better," Bachchan posted on his blog.
Actor-director Farhan also took to twitter to share his excitement about the film and working with Bachchan.
"A new experience awaits on the other side of this night.. First day on sets of 'Do'.. Look forward. Peace out,"the 'Bhaag Milkha Bhaag' star wrote.